RAF Typhoon FGR4s have operated alongside French aircraft in a combined operation on an underground arms cache in Syrian territory operated by the Islamic State group (IS), per a report from the UK's MoD.
The facility, located using reconnaissance, was assessed as storing arms and explosives, the statement said, and was situated in hills just above the historic site of Palmyra in central Syria.
"The RAF jets employed precision-guided Paveway IV munitions to target a number of approach shafts down to the depot... early reports indicate the objective was successfully hit," the MoD said.
There was no evidence of any harm to civilians in the attack conducted Saturday night and all the aircraft made a safe return, the MoD added.
The Typhoon fighters were backed up by a Voyager tanker plane.
The Islamic State group - also known as the so-called Islamic State - established militant control over parts of Iraq and Syria before its territorial defeat in 2019.
"This operation demonstrates our UK leadership, and resolve to stand shoulder to shoulder with allied nations, to stamp out any re-emergence of the terrorist group and their violent and radical beliefs in the Middle East," Britain's Defence Chief the Defence Secretary said.
UK warplanes have carried out surveillance missions over Syria to "forestall any efforts to regroup" of the group after its military defeat at the climactic battle in Baghuz in 2019, the authorities noted.
"I extend gratitude to the personnel of British forces participating in this strike for their professionalism and their valour," the Defence Secretary commented. "They were among thousands of British personnel on duty over the festive period. This action, to take out dangerous terrorists who threaten our safety, demonstrates how British military are always on standby, throughout the year, ensuring Britain's security within its borders and powerful internationally."
Last December, the US military executed what it termed a "major assault" against Daesh sites in the country, subsequent to an assault killed two American soldiers and a civilian interpreter in Palmyra.
The UN reports Daesh still maintains an estimated 5,000 to 7,000 militants in both countries.